MECHANISM OF ACTION (MOA)

The mechanism of action/pharmacodynamics of ELIDEL Cream and the inflammatory cascade.6,8

Targets Cells Involved in Skin InfIammation

  • The mechanism of action of ELIDEL Cream in eczema is unknown.6
  • In vitro, it has been demonstrated that pimecrolimus inhibits calcineurin and thus inhibits
    T cell activation by blocking the transcription of inflammatory cytokines.6,8*
  • Pimecrolimus has an immunosuppressant action and targets cells involved in skin inflammation.6

*The clinical significance of in vitro data has not been established.

With ELIDEL, systemic absorption of pimecrolimus is low. Learn More.